3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acid → HCID 69584070, compound

HRID 1826762Notes

Reaction equation

HRID 1826762 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH:17]([C:19]1[NH:20][C:21]([CH3:29])=[CH:22][C:23]=1[CH2:24][CH2:25][C:26]([OH:28])=[O:27])=O>>[CH3:29][C:21]1[NH:20][C:19]([CH:17]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[CH:4]3[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]3)[NH:11][C:10]2=[O:16])=[C:23]([CH2:24][CH2:25][C:26]([OH:28])=[O:27])[CH:22]=1

Participants

3

Reactant 2

HCID 221353943-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acidHCID 221353964-(Piperidin-4-yl)indolin-2-one

Product 1

HCID 69584070HCID 69584070, compound

Procedure

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 3-(2-formyl-5-methyl-1H-pyrrol-3-yl)-propionic acid (42 mg, 0.23 mmol) to give the title compound.

Sources & evidence

ORD record
ord-a1a8b837d8cd4d92b5a317df00f75f75
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

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