4-(Piperidin-4-yl)indolin-2-one → HCID 24942413, compound

HRID 1826763Notes

Reaction equation

HRID 1826763 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH2:17]([C:19]1[NH:23][C:22]([CH:24]=O)=[C:21]([CH2:26][CH2:27][C:28]([OH:30])=[O:29])[CH:20]=1)[CH3:18]>>[CH2:17]([C:19]1[NH:23][C:22]([CH:24]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[CH:4]3[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]3)[NH:11][C:10]2=[O:16])=[C:21]([CH2:26][CH2:27][C:28]([OH:30])=[O:29])[CH:20]=1)[CH3:18]

Participants

3

Reactant 2

HCID 221353964-(Piperidin-4-yl)indolin-2-oneHCID 22135424HCID 22135424, compound

Product 1

HCID 24942413HCID 24942413, compound

Procedure

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 3-(5-ethyl-2-formyl-1H-pyrrol-3-yl)-propionic acid (0.23 mmol) to give the title compound.

Sources & evidence

ORD record
ord-26262e98f66e47bfbe0fad9cbdde5100
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

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