5-formyl-4-methyl-1H-pyrrole-2-carboxylic Acid → HCID 69584075, compound

HRID 1826770Notes

Reaction equation

HRID 1826770 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH:17]([C:19]1[NH:23][C:22]([C:24]([OH:26])=[O:25])=[CH:21][C:20]=1[CH3:27])=O>>[CH3:27][C:20]1[CH:21]=[C:22]([C:24]([OH:26])=[O:25])[NH:23][C:19]=1[CH:17]=[C:9]1[C:8]2[C:12](=[CH:13][CH:14]=[CH:15][C:7]=2[CH:4]2[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]2)[NH:11][C:10]1=[O:16]

Participants

3

Reactant 2

HCID 98988845-formyl-4-methyl-1H-pyrrole-2-carboxylic AcidHCID 221353964-(Piperidin-4-yl)indolin-2-one

Product 1

HCID 69584075HCID 69584075, compound

Procedure

4-Piperidin-4-yl-1,3-dihydro-indol-2-one (45 mg, 0.2 mmol) was condensed with 5-formyl-4-methyl-1H-pyrrole-2-carboxylic acid (34 mg, 0.23 mmol) to give the title compound.

Sources & evidence

ORD record
ord-7d42cd7e926f49d9a3bd39815885c19d
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

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