HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[5-(Ethoxycarbonyl)-2-formyl-4-methyl-1H-pyrrol-3-yl]propanoic acid → 4-(2-Carboxyethyl)-3-methyl-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[5-(Ethoxycarbonyl)-2-formyl-4-methyl-1H-pyrrol-3-yl]propanoic acid | HCID 15270623 | — |
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Product | 4-(2-Carboxyethyl)-3-methyl-5-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-2-carboxylic Acid Ethyl Ester | HCID 24941217 | — |
Reaction Steps
4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 4-(2-carboxyethyl)-5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid ethyl ester (55 mg, 0.23 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053086B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-a7144034a4f44b2ea6c2827f8adcb8ad |
| Source note | uspto-grants-2006_05 |