4-(Piperidin-4-yl)indolin-2-one → HCID 69584139, compound

HRID 1826780Notes

Reaction equation

HRID 1826780 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH:17]([C:19]1[NH:23][CH:22]=[C:21]([C:24]([OH:26])=[O:25])[C:20]=1[CH2:27][CH2:28][OH:29])=O>>[OH:29][CH2:28][CH2:27][C:20]1[C:21]([C:24]([OH:26])=[O:25])=[CH:22][NH:23][C:19]=1[CH:17]=[C:9]1[C:8]2[C:12](=[CH:13][CH:14]=[CH:15][C:7]=2[CH:4]2[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]2)[NH:11][C:10]1=[O:16]

Participants

3

Reactant 2

HCID 221353964-(Piperidin-4-yl)indolin-2-oneHCID 22135484HCID 22135484, compound

Product 1

HCID 69584139HCID 69584139, compound

Procedure

A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one was condensed with 5-formyl-4-(2-hydroxyethyl)-1H-pyrrole-3-carboxylic acid to give the title compound.

Sources & evidence

ORD record
ord-483fc3b86cb84a9ab6938d501eba7fac
Source dataset
uspto-grants-2006_05
Patent number
US07053086B2

Reaction notes

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