Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1826787Generated: October 27, 2026

3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde → 3-[3,5-Dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-pyrimidin-5-yl-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/1826787

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehydeHCID 12111582—
Reactant4-Pyrimidin-5-yl-1,3-dihydroindol-2-oneHCID 22135400—
Product3-[3,5-Dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-4-pyrimidin-5-yl-1,3-dihydroindol-2-oneHCID 24942408—

Reaction Steps

4-Pyrimidin-5-yl-1,3-dihydroindol-2-one (53 mg, 0.25 mmol) was condensed with 3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (69 mg, 0.275 mmol) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053086B2
Source datasetuspto-grants-2006_05
ORD IDord-2be4e4cce6ab45b492e0a9b46caea4f1
Source noteuspto-grants-2006_05