HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(6-Aminopyridin-3-yl)-1,3-dihydroindol-2-one → 5-[4-(6-Aminopyridin-3-yl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-2-methyl-4-[3-(4-methylpiperazin-1-yl)propyl]1H-pyrrole-3-carboxylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(6-Aminopyridin-3-yl)-1,3-dihydroindol-2-one | HCID 22135432 | — |
| Reactant | 5-formyl-2-methyl-4-[3-(4-methylpiperazin-1-yl)propyl]-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 58779587 | — |
| Product | 5-[4-(6-Aminopyridin-3-yl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-2-methyl-4-[3-(4-methylpiperazin-1-yl)propyl]1H-pyrrole-3-carboxylic Acid Ethyl Ester | HCID 69584160 | — |
Reaction Steps
4-(6-Aminopyridin-3-yl)-1,3-dihydroindol-2-one (56 mg, 0.25 mmol) was condensed with 5-formyl-2-methyl-4-[3-(4-methyl-piperazin-1-yl)propyl]-1H-pyrrole-3-carboxylic acid ethyl ester (88 mg, 0.275 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053086B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-b06f725d703b41288394fecc25a7121e |
| Source note | uspto-grants-2006_05 |