HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Quinolin-7-yl-[6-(1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-[6-(Quinolin-7-ylamino)-pyrimidin-4-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester | HCID 23577236 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Quinolin-7-yl-[6-(1,2,3,6-tetrahydro-pyridin-4-yl)-pyrimidin-4-yl)-amine | HCID 22135542 | — |
Reaction Steps
This compound could be prepared from 4-[6-(quinolin-7-ylamino)-pyrimidin-4-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester in the presence of TFA and CH2Cl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053088B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-bb83dc36b5b744cba7c62f86498a5414 |
| Source note | uspto-grants-2006_05 |