Malononitrile → HCID 14168963, compound

Participants

Reaction Steps

3-Cyano-2-imino-4-phenyl-2H-chromene. To a mixture of 2-hydroxybenzophenone (2.0 g, 10 mmol) and malononitrile (661 mg, 10 mmol) in ethanol (15 mL) was added piperidine (0.5 mL, 5.0 mmol). The mixture was stirred under 0–5° C. for 2 h. The solvent was evaporated and the residue was purified by chromatography on silica gel with ethyl acetate and hexane (1:2) as eluant, yielding 1.2 g (8%) of the title compound. 1H NMR (CDCl3): 7.74–7.29 (m, 7H), 7.20–7.13 (m, 2H).

Provenance & Evidence