HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malononitrile → HCID 69620633, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | 1H-indol-4-ol | HCID 75421 | — |
| Reactant | 6-Methylpyrazine-2-carbaldehyde | HCID 22136797 | — |
| Product | HCID 69620633 | HCID 69620633 | 22% |
Reaction Steps
The title compound was prepared from 6-methyl-pyrazine-2-carbaldehyde, malononitrile and 4-hydroxyindole by a procedure similar to Example 57 in 22% yield. 1-NMR (DMSO-d6): 11.30 (brs, 1H), 8.44 (dd, J=15.6, 1.10 Hz, 2H), 7.36 (dd, J=3.03, 0.83 Hz, 1H), 7.09 (d, J=8.51 Hz, 1H), 7.00 (s, 2H), 6.69 (d, J=8.24 Hz, 1H), 6.45 (m, J=3.03, 1.10, 0.83 Hz, 1H), 4.97 (s, 1H), 2.44 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053117B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-bf9a7be609e340a8939b5496ce1c5ec3 |
| Source note | uspto-grants-2006_05 |