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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1826982Generated: October 31, 2026

Malononitrile → HCID 69620621, compound

https://huagongshe.com/reaction/1826982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalononitrileHCID 8010—
Reactant7-HydroxyindoleHCID 2737651—
Reactant5-Formylpyridine-3-carbonitrileHCID 12919806—
ProductHCID 69620621HCID 6962062159%

Reaction Steps

The title compound was prepared from 5-formyl-nicotinonitrile, malononitrile and 7-hydroxyindole by a procedure similar to Example 57 in 59% yield. 1H-NMR (Acetone-d6): 10.54 (brs, 1H), 8.84 (m, J=2.20, 1.90 Hz, 2H), 8.12 (t, J=2.20, 1.90 Hz, 1H), 7.39 (m, J=3.03 Hz, 1H), 7.32 (dd, J=8.00 Hz, 1H), 6.68 (dd, J=8.20 Hz, 1H), 6.51 (m, J=3.03 Hz, 1H), 6.22 (s, 2H), 5.13 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053117B2
Source datasetuspto-grants-2006_05
ORD IDord-d1a3abf823da4117bc0f19610c1cbe25
Source noteuspto-grants-2006_05