HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malononitrile → HCID 69620615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | 7-Hydroxyindole | HCID 2737651 | — |
| Reactant | 6-Methylpyrazine-2-carbaldehyde | HCID 22136797 | — |
| Product | HCID 69620615 | HCID 69620615 | 82% |
Reaction Steps
The title compound was prepared from 6-methyl-pyrazine-2-carbaldehyde, malononitrile and 7-hydroxyindole by a procedure similar to Example 57 in 82% yield. 1H-NMR (DMSO-d6): 10.43 (brs, 1H), 8.50 (d, J=1.37 Hz, 1H), 8.38 (d, J=0.82 Hz, 1H), 7.35 (m, J=2.47, 2.20, 1.10, 0.83 Hz, 1H), 7.27 (d, J=8.24 Hz, 1H), 6.72 (dd, J=8.24, 0.55 Hz, 1H), 6.47 (m, J=2.20, 0.55 Hz, 1H), 6.11 (brs, 2H), 5.05 (s, 1H), 2.47 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053117B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-90d22ea5942a48ea862d82c18259e2d1 |
| Source note | uspto-grants-2006_05 |