HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide → 5-[6-(2,4-Dimethoxyphenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide | HCID 20761729 | — |
| Reactant | 6-(2,4-Dimethoxyphenyl)-1,3-dihydroindol-2-one | HCID 21915616 | — |
| Product | 5-[6-(2,4-Dimethoxyphenyl)-2-oxo-1,2-dihydroindol-3-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide | HCID 67280888 | 31% |
Reaction Steps
6-(2,4-Dimethoxyphenyl)-1,3-dihydroindol-2-one (51 mg, 0.19 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide (50 mg) to give 30 mg (31%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053114B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-f1499f31fdfe439ca43b2abe260e037d |
| Source note | uspto-grants-2006_05 |