Borane → HCID 178525135, compound

HRID 1827115Notes

Reaction equation

HRID 1827115 reaction equation
[O-:1][N+:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([CH:11]2[CH2:16][CH2:15][N:14]([C:17]([O:19][CH2:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:18])[CH2:13][CH2:12]2)=O)=[CH:4][CH:3]=1.B>>[O-:1][N+:2]1[CH:3]=[CH:4][C:5]([NH:8][CH2:9][CH:11]2[CH2:16][CH2:15][N:14]([C:17]([O:19][CH2:20][C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)=[O:18])[CH2:13][CH2:12]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6331BoraneHCID 178522349HCID 178522349, compound

Product 1

HCID 178525135HCID 178525135, compound

Procedure

Benzyl 4-{[(1-oxido-4-pyridinyl)amino]carbonyl}-1-piperidinecarboxylate (62 mg, 0.17 mmol) was reduced with borane as described in EXAMPLE 1, step 2, to afford benzyl 4-{[(1-oxido-4-pyridinyl)amino]methyl}-1-piperidinecarboxylate as a clear oil.

Sources & evidence

ORD record
ord-c29ff690f6fd45c9ade20d3f991b0a29
Source dataset
uspto-grants-2006_05
Patent number
US07053089B2

Reaction notes

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