HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → 4-Methylbenzyl 4-[(2-pyrimidinylamino)methyl]-1-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | 4-Methylbenzyl 4-(aminomethyl)1-piperidinecarboxylate | HCID 16109417 | — |
| Product | 4-Methylbenzyl 4-[(2-pyrimidinylamino)methyl]-1-piperidinecarboxylate | HCID 9881090 | — |
Reaction Steps
The title compound was prepared as described in EXAMPLE 13, except using 4-methylbenzyl 4-(aminomethyl)-1-piperidinecarboxylate (300 mg, 1.14 mmol), 2-chloropyrimidine (131 mg, 1.14 mmol) as starting materials gave the title compound as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-7e8f4f9d7744453aaec15177a6d6529f |
| Source note | uspto-grants-2006_05 |