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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827193Generated: November 1, 2026

7H-Purine, 6-chloro-7-methyl- → (7-Methyl-7H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine

https://huagongshe.com/reaction/1827193

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7H-Purine, 6-chloro-7-methyl-HCID 95057—
Reactant[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamineHCID 22135729—
Product(7-Methyl-7H-purin-6-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amineHCID 23577259—

Reaction Steps

EXAMPLE 85 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 6-chloro-7-methyl-7H-purine (6-chloro-7-methyl-7H-purine was prepared according to G. B. Eilon, J. Org. Chem., 27:2478–2491 (1962): MS (m+1)=415.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053089B2
Source datasetuspto-grants-2006_05
ORD IDord-08a418cef8fe41a097c34e11ffa0aa17
Source noteuspto-grants-2006_05