Pyrimidine, 2,4-dichloro-5-methyl- → HCID 23577242, compound

HRID 1827199Notes

Reaction equation

HRID 1827199 reaction equation
[C:1]1([CH2:7][CH2:8][S:9]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][NH2:19])[CH2:14][CH2:13]2)(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:20][C:21]1[N:26]=[C:25](Cl)[C:24]([CH3:28])=[CH:23][N:22]=1>>[Cl:20][C:21]1[N:26]=[C:25]([NH:19][CH2:18][CH:15]2[CH2:14][CH2:13][N:12]([S:9]([CH2:8][CH2:7][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)(=[O:10])=[O:11])[CH2:17][CH2:16]2)[C:24]([CH3:28])=[CH:23][N:22]=1

Participants

3

Reactant 2

HCID 74508Pyrimidine, 2,4-dichloro-5-methyl-HCID 22135729[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamine

Product 1

HCID 23577242HCID 23577242, compound

Procedure

EXAMPLE 91 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2,4-dichloro-5-methyl-pyrimidine: MS (m+1)=410.

Sources & evidence

ORD record
ord-665e59b5573d45a88c0ba211a227d62c
Source dataset
uspto-grants-2006_05
Patent number
US07053089B2

Reaction notes

Loading…