HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloropyrimidine → HCID 23577295, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | [1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamine | HCID 22135729 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | EtOH triethylamine | HCID 22663003 | — |
| Product | HCID 23577295 | HCID 23577295 | — |
Reaction Steps
EXAMPLE 93 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2,4-dichloro-pyrimidine followed by hydrogenation in ethanol-triethylamine over 5% palladium on carbon, 1 atm of hydrogen: MS (m+1)=361.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-b468aea35a5b461da471c9412483c378 |
| Source note | uspto-grants-2006_05 |