2-Chloro-4-methylpyrimidine → HCID 23577254, compound

HRID 1827202Notes

Reaction equation

HRID 1827202 reaction equation
[C:1]1([CH2:7][CH2:8][S:9]([N:12]2[CH2:17][CH2:16][CH:15]([CH2:18][NH2:19])[CH2:14][CH2:13]2)(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[C:21]1[N:26]=[C:25]([CH3:27])[CH:24]=[CH:23][N:22]=1>>[CH3:27][C:25]1[CH:24]=[CH:23][N:22]=[C:21]([NH:19][CH2:18][CH:15]2[CH2:14][CH2:13][N:12]([S:9]([CH2:8][CH2:7][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)(=[O:10])=[O:11])[CH2:17][CH2:16]2)[N:26]=1

Participants

3

Reactant 2

HCID 116296072-Chloro-4-methylpyrimidineHCID 22135729[1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamine

Product 1

HCID 23577254HCID 23577254, compound

Procedure

EXAMPLE 94 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 2-chloro-4-methyl-pyrimidine: MS (m+1)=375.5.

Sources & evidence

ORD record
ord-25be20878f1f4767b466e85f7fac4c57
Source dataset
uspto-grants-2006_05
Patent number
US07053089B2

Reaction notes

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