HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium tri-s-butylborohydride → HCID 23577246, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium tri-s-butylborohydride | HCID 3611392 | — |
| Reactant | Methyl 3-bromopyrazine-2-carboxylate | HCID 13318551 | — |
| Reactant | [1-(2-Phenylethylsulfonyl)piperidin-4-yl]methanamine | HCID 22135729 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23577246 | HCID 23577246 | — |
Reaction Steps
EXAMPLE 97 was prepared from C-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-yl]-methylamine and 3-bromo-pyrazine-2-carboxylic acid methyl ester followed by reduction with lithium tri-sec-butylborohydride at 0° C. in THF: MS (m+1)=375.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-f9c8f9ab984846dab7982583901896b4 |
| Source note | uspto-grants-2006_05 |