Benzyl 3-(aminomethyl)pyrrolidine-1-carboxylate → HCID 178525137, compound

HRID 1827207Notes

Reaction equation

HRID 1827207 reaction equation
[CH2:1]([O:8][C:9]([N:11]1[CH2:15][CH2:14][CH:13]([CH2:16][NH2:17])[CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:19]1[N:27]=[CH:26][N:25]=[C:24]2[C:20]=1[N:21]=[CH:22][NH:23]2>>[CH2:1]([O:8][C:9]([N:11]1[CH2:15][CH2:14][CH:13]([CH2:16][NH:17][C:19]2[N:27]=[CH:26][N:25]=[C:24]3[C:20]=2[N:21]=[CH:22][NH:23]3)[CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 15550581Benzyl 3-(aminomethyl)pyrrolidine-1-carboxylateHCID 178478393HCID 178478393, compound

Product 1

HCID 178525137HCID 178525137, compound

Procedure

EXAMPLE 102 was prepared from 3-aminomethyl-pyrrolidine-1-carboxylic acid benzyl ester (EXAMPLE 79, Step 3) and 6-chloro-9H-purine: MS (m+1)=353.4.

Sources & evidence

ORD record
ord-2028ca14b6724ae58c0a1631a11997d0
Source dataset
uspto-grants-2006_05
Patent number
US07053089B2

Reaction notes

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