2,3-Dichloropyrazine → HCID 23577300, compound

HRID 1827214Notes

Reaction equation

HRID 1827214 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[N:6][CH:5]=[CH:4][N:3]=1.[CH3:9][C:10]1[CH:27]=[CH:26][C:13]([CH2:14][O:15][C:16]([N:18]2[CH2:23][CH2:22][CH:21]([CH2:24][NH2:25])[CH2:20][CH2:19]2)=[O:17])=[CH:12][CH:11]=1>>[CH3:9][C:10]1[CH:11]=[CH:12][C:13]([CH2:14][O:15][C:16]([N:18]2[CH2:23][CH2:22][CH:21]([CH2:24][NH:25][C:2]3[C:7]([Cl:8])=[N:6][CH:5]=[CH:4][N:3]=3)[CH2:20][CH2:19]2)=[O:17])=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 785752,3-DichloropyrazineHCID 161094174-Methylbenzyl 4-(aminomethyl)1-piperidinecarboxylate

Product 1

HCID 23577300HCID 23577300, compound

Procedure

The title compound was prepared as described in EXAMPLE 47, reacting 2,3-dichloropyrazine with INTERMEDIATE 2a to give the title compound. M.S.(M+1): 375.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-37a9059a09204610adba8e0641ce88b2
Source dataset
uspto-grants-2006_05
Patent number
US07053089B2

Reaction notes

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