HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,5-dimethylpyrimidine → 4-[(4,5-Dimethyl-pyrimidin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,5-dimethylpyrimidine | HCID 12581784 | — |
| Reactant | 4-Methylbenzyl 4-(aminomethyl)1-piperidinecarboxylate | HCID 16109417 | — |
| Product | 4-[(4,5-Dimethyl-pyrimidin-2-ylamino)-methyl]-piperidine-1-carboxylic acid 4-methyl-benzyl ester | HCID 23577303 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4,5-dimethylpyrimidine (EXAMPLE 148, STEP 1) and INTERMEDIATE 2A as described in a manner similar to that described in EXAMPLE 144, STEP 2 to give the title compound. M.S.(M+1): 369
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-d2d079d17eb44af1aa881819f2b86117 |
| Source note | uspto-grants-2006_05 |