HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Fluorobenzyloxy)-4-nitro-benzene → 4-(3-Fluoro-benzyloxy)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Fluorobenzyloxy)-4-nitro-benzene | HCID 22137915 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
Reaction Steps
3 g (12.1 mmol) of 1-(3-fluorobenzyloxy)-4-nitro-benzene is dissolved in 125 ml of methanol. 150 mg of Pt 5% on charcoal is added and hydrogenation done under normal pressure for about 17 h. The catalyst is filtered and the solution evaporated to yield 2.51 g (95%) of crude brownish material. MS: m/e=218.4 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053245B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-2f7f4def05c9410da806d0549399a08a |
| Source note | uspto-grants-2006_05 |