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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827366Generated: October 25, 2026

Ammonium Hydroxide → N-[4-(3-Fluoro-benzyloxy)-phenyl]-2-methyl-malonamide

https://huagongshe.com/reaction/1827366

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantN-[4-(3-Fluoro-benzyloxy)-phenyl]-2-methyl-malonamic Acid Methyl EsterHCID 69008808—
ProductN-[4-(3-Fluoro-benzyloxy)-phenyl]-2-methyl-malonamideHCID 9973047—

Reaction Steps

The title compound is prepared in analogy to example 3 from N-[4-(3-fluoro-benzyloxy)-phenyl]-2-methyl-malonamic acid methyl ester and ammonium hydroxide. Colorless solid. Mp=206° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053245B2
Source datasetuspto-grants-2006_05
ORD IDord-160374cb0db44ebcadda43ea1c9e081b
Source noteuspto-grants-2006_05