HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethoxy-2,2-dimethyl-3-oxopropanoic acid → HCID 69007672, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethoxy-2,2-dimethyl-3-oxopropanoic acid | HCID 231754 | — |
| Reactant | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| Solvent | Cyclohexane ethylacetate | HCID 21867204 | — |
| Product | HCID 69007672 | HCID 69007672 | — |
Reaction Steps
The title compound is prepared in analogy to example 2, starting from 4-(3-fluoro-benzyloxy)-phenylamine and 2,2-dimethyl-malonic acid monoethyl ester (Holmes et al., J. Amer. Chem. Soc. 1984, 106, 2353). Yield after flash-chromatography with cyclohexane/ethyl acetate 7:3: 79%. Colorless oil. MS: m/e=359 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053245B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-916bd91f46c34cac8429b30b79e5478f |
| Source note | uspto-grants-2006_05 |