HCID 21920014, compound → HCID 21920051, compound

HRID 1827382Notes

Reaction equation

HRID 1827382 reaction equation
FC1C=C(N)C=CC=1OCC1C=CC=C(F)C=1.[F:18][C:19]1[CH:24]=[C:23]([O:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)[CH:22]=[CH:21][C:20]=1[N+:34]([O-])=O>>[F:18][C:19]1[CH:24]=[C:23]([O:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)[CH:22]=[CH:21][C:20]=1[NH2:34]

Participants

3

Reactant 2

HCID 21920014HCID 21920014, compoundHCID 219200533-Fluoro-4-[(3-fluorophenyl)methoxy]benzenamine

Product 1

HCID 21920051HCID 21920051, compound

Procedure

The title compound is prepared in analogy to 3-fluoro-4-(3-fluoro-benzyloxy)-phenylamine by hydrogenation of 2-Fluoro-4-(3-fluoro-benzyloxy)-nitrobenzene. Yield: 98% of a dark brown oil. MS: m/e=235.0 (M+).

Sources & evidence

ORD record
ord-2fab1c3d40a74ca6a00072f5b4fecff1
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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