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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827388Generated: October 31, 2026

Ammonium Hydroxide → N-[4-(3-Fluoro-phenoxymethyl)-phenyl]-malonamide

https://huagongshe.com/reaction/1827388

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantN-[4-(3-Fluoro-phenoxymethyl)-phenyl]-malonamic Acid Methyl EsterHCID 69006710—
ProductN-[4-(3-Fluoro-phenoxymethyl)-phenyl]-malonamideHCID 2213797837%

Reaction Steps

The title compound is prepared in analogy to example 3 from N-[4-(3-Fluoro-phenoxymethyl)-phenyl]-malonamic acid methyl ester and and ammonium hydroxide. Yield=37%. Colorless solid. MS: m/e=303.2 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053245B2
Source datasetuspto-grants-2006_05
ORD IDord-7a58fbf1e58e4f058021e506f56113b4
Source noteuspto-grants-2006_05