113137-33-0 → HCID 69007532, compound

HRID 1827390Notes

Reaction equation

HRID 1827390 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][CH:8]=1.[CH3:17][O:18][C:19](=[O:26])[CH:20]([O:24][CH3:25])[C:21](O)=[O:22]>>[CH3:17][O:18][C:19](=[O:26])[CH:20]([O:24][CH3:25])[C:21]([NH:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]2[CH:14]=[CH:15][CH:16]=[C:2]([F:1])[CH:3]=2)=[CH:8][CH:9]=1)=[O:22]

Participants

3

Reactant 2

HCID 15004075113137-33-0HCID 167753144-(3-Fluoro-benzyloxy)-phenylamine

Product 1

HCID 69007532HCID 69007532, compoundYield 41%

Procedure

The title compound is prepared in analogy to example 2 from 4-(3-Fluoro-benzyloxy)-phenylamine and 2-methoxy-malonic acid monomethyl ester (Swan et al.; J. Chem. Soc. Perkin Trans. 1; 1985; 1757-1766). Yield=41%. Colorless solid. MS: m/e=348.2 (M++H).

Sources & evidence

ORD record
ord-0115cf77f2e94768bd1f341ffcdaf524
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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