Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827391Generated: October 26, 2026

4-Nitro-3-trifluoromethylphenol → 4-(3-Fluoro-benzyloxy)-1-nitro-2-trifluoromethyl-benzene

https://huagongshe.com/reaction/1827391

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitro-3-trifluoromethylphenolHCID 6931—
Reactant3-Fluorobenzyl bromideHCID 68007—
Product4-(3-Fluoro-benzyloxy)-1-nitro-2-trifluoromethyl-benzeneHCID 2213796385%

Reaction Steps

Prepared in analogy to example 8 from 4-nitro-3-(trifluoromethyl)-phenol and 3-Fluoro-benzylbromide. Yield=85%. Yellowish solid. MS (ISP): m/e=333.2 (M++NH4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053245B2
Source datasetuspto-grants-2006_05
ORD IDord-36c9b3c82f3f4eb4be7c7471c86524dc
Source noteuspto-grants-2006_05