4-Nitrophenol → HCID 22137903, compound

HRID 1827405Notes

Reaction equation

HRID 1827405 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]([OH:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[N+:11]([C:14]1[CH:19]=[CH:18][C:17](O)=[CH:16][CH:15]=1)([O-:13])=[O:12]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH:8]([O:10][C:17]2[CH:18]=[CH:19][C:14]([N+:11]([O-:13])=[O:12])=[CH:15][CH:16]=2)[CH3:9])[CH:3]=1

Participants

3

Reactant 2

HCID 9804-NitrophenolHCID 953483-Fluoro-alpha-methylbenzenemethanol

Product 1

HCID 22137903HCID 22137903, compoundYield 77%

Procedure

Prepared in analogy to example 16a) from 1-(3-fluoro-phenyl)-ethanol (Balasubramanian et al., Synth. Commun., 1994, 24 (8), 1049) and 4-nitrophenol. Yellow oil. Yield=77%. MS: m/e=261.2 (M+).

Sources & evidence

ORD record
ord-d9589ced16434b7b9a9e2cd313703f57
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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