1-(Bromomethyl)-4-chlorobenzene → HCID 10426064, compound

HRID 1827409Notes

Reaction equation

HRID 1827409 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:14])[CH2:10][C:11]([NH2:13])=[O:12])=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20]Br)=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][O:1][C:2]2[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:14])[CH2:10][C:11]([NH2:13])=[O:12])=[CH:6][CH:7]=2)=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 693291-(Bromomethyl)-4-chlorobenzeneHCID 22137894HCID 22137894, compound

Product 1

HCID 10426064HCID 10426064, compoundYield 18%

Procedure

Prepared in analogy to example 8 from N-(4-hydroxy-phenyl)-malonamide and 4-chloro-benzylbromide. Colorless solid. Yield=18%. MS: m/e=319.1 (M++H).

Sources & evidence

ORD record
ord-4b3eb21265f64cb2aec801d88c163693
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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