Ammonia → HCID 10019937, compound

HRID 1827423Notes

Reaction equation

HRID 1827423 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=2)=[C:10]([Cl:23])[CH:9]=1)=[O:6].[NH3:25]>CO>[Cl:23][C:10]1[CH:9]=[C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:25])=[O:2])[CH:13]=[CH:12][C:11]=1[O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 10338039HCID 10338039, compound

Product 1

HCID 10019937HCID 10019937, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared in analogy to example 3 from N-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-malonamic acid methyl ester and 7M ammonia in methanol. Yield=100%. Colorless solid. MS: m/e=337.1 (M++H).

Sources & evidence

ORD record
ord-666b88d72c27423faeecf99eaf397afa
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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