5-Nitrosalicylaldehyde → 2-((3-Fluorobenzyl)oxy)-5-nitrobenzaldehyde

HRID 1827425Notes

Reaction equation

[OH:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:4]=[O:5].[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=1)[CH2:17]Br>>[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=1)[CH2:17][O:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:4]=[O:5]

Participants

Reactant 2

HCID 668085-Nitrosalicylaldehyde

HCID 680073-Fluorobenzyl bromide

Product 1

HCID 27795602-((3-Fluorobenzyl)oxy)-5-nitrobenzaldehydeYield 95%

Procedure

Prepared in analogy to example 8 from 2-hydroxy-5-nitrobenzaldehyde and 3-fluoro-benzylbromide. Colorless solid. Yield=95%. MS: m/e=275.1 (M+).

Sources & evidence

ORD record: ord-c52577e6b9b84038bfff580166e7a30c
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07053245B2

Reaction notes

Loading…