Ammonia → HCID 22137961, compound

HRID 1827438Notes

Reaction equation

HRID 1827438 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[CH:10][CH:9]=1)=[O:6].[NH3:24]>CO>[Cl:22][C:19]1[CH:20]=[CH:21][C:16]([CH2:15][CH2:14][C:11]2[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:24])=[O:2])=[CH:9][CH:10]=2)=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 69007381HCID 69007381, compound

Product 1

HCID 22137961HCID 22137961, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared in analogy to example 3 from N-{4-[2-(4-chloro-phenyl)-ethyl]-phenyl}-malonamic acid methyl ester and 7M ammonia in methanol. Yield=65%. Colorless solid. MS: m/e=317.1 (M++H).

Sources & evidence

ORD record
ord-74adfe5f065845bab0d7a42e7be1f4ff
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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