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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 182747Generated: October 25, 2026

Diethyl Ether → 2,2-Difluoro-1-(2-fluoro-4-methoxyphenyl)ethan-1-one

https://huagongshe.com/reaction/182747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantEthyl difluoroacetateHCID 9961—
Reactant1-Bromo-2-fluoro-4-methoxybenzeneHCID 3718444—
ReactantButyllithiumHCID 178418339—
Product2,2-Difluoro-1-(2-fluoro-4-methoxyphenyl)ethan-1-oneHCID 86638491—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-854a71864e2c4e56946e32b7cb44e9b0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)