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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18276Generated: October 25, 2026

5-methoxy-1-methyl-1H-indole-3-carbaldehyde → 1-(5-Methoxy-1-methyl-1H-indol-3-yl)-N-methylmethanamine

https://huagongshe.com/reaction/18276

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-methoxy-1-methyl-1H-indole-3-carbaldehydeHCID 925973—
Reactant1,3-dimethyl-1H-indole-2-carbaldehydeHCID 2771468—
ReactantMethyl 2-((5-bromopyridin-2-yl)amino)acetateHCID 22139049—
Product1-(5-Methoxy-1-methyl-1H-indol-3-yl)-N-methylmethanamineHCID 1228388298%

Reaction Steps

According to the procedure of Preparation 13 (c), except substituting 5-methoxy-1-methyl-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.85 g, 98%) was obtained as a light yellow oil: MS (ES) m/e 205.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741339B2
Source datasetuspto-grants-2010_06
ORD IDord-a0a8d5a420004846b85b90df8251267c
Source noteuspto-grants-2010_06