Diphenylamine → N-[(2,4-Diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]-N,N-diphenylamine

Participants

Reaction Steps

X=N; W=CH2; Z=non-linked hydrogens on each phenyl group; Z=CH2; m=n=0) is prepared similarly as disclosed in Example 1 above by using N,N-diphenylamine (1.3 g, 0.77 mmol), NaH (50 mg, 2.1 mmol), and 2,4-diamino-6-bromomethylpyrido[2,3-d]pyrimidine hydrobromide (100 mg, 0.3 mmol). The product can be purified by chromatography.

Provenance & Evidence