HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibenz(b,f)azepine → HCID 446744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibenz(b,f)azepine | HCID 9212 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 6-[(N-phenylanilino)methyl]pteridine-2,4-diamine | HCID 486242 | — |
| Reactant | 6-(Bromomethyl)-2-imino-2,3-dihydropteridin-4-amine--hydrogen bromide (1/1) | HCID 12503242 | — |
| Product | HCID 446744 | HCID 446744 | — |
Reaction Steps
N-[(2,4-Diaminopteridin-6-yl)methyl]dibenz[b,f]azepine (Formula I: Ar=2,4-diaminopteridin-6-yl; W=CH2; X=N; Z=CH═CH; m=n=0) is prepared similarly to N-[(2,4-diaminopteridin-6-yl)methyl]-N,N-diphenylamine as disclosed above, by using dibenz[b,f]azepine (154 mg, 0.8 mmol), NaH (50 mg, 2.1 mmol), and 2,4-diamino-6-bromomethylpteridine hydrobromide (100 mg, 0.3 mmol). The product can be purified by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07056911B1 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-22cda088184f4efa86258599a2c0a950 |
| Source note | uspto-grants-2006_06 |