Ethyl 2-chloro-2-ethoxyacetate → HCID 69642566, compound

HRID 1828101Notes

Reaction equation

HRID 1828101 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4](=[O:12])[NH:5][C:6]2=[O:11].[CH2:13]([O:15][C:16](=[O:22])[CH:17](Cl)[O:18][CH2:19][CH3:20])[CH3:14]>>[CH2:13]([O:15][C:16](=[O:22])[CH:17]([O:18][CH2:19][CH3:20])[N:5]1[C:4](=[O:12])[C:3]2[C:7](=[CH:8][CH:9]=[CH:10][C:2]=2[F:1])[C:6]1=[O:11])[CH3:14]

Participants

3

Reactant 2

HCID 2724873Ethyl 2-chloro-2-ethoxyacetateHCID 220646324-Fluoro-1H-isoindole-1,3(2H)-dione

Product 1

HCID 69642566HCID 69642566, compound

Procedure

According to general procedure H, 4-fluoro-1H-isoindole-1,3(2H)-dione (CAS51108-29-3) was reacted with 2-chloro-2-ethoxyacetic acid ethyl ester to give (RS)-ethoxy-(4-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetic acid ethyl ester, MS 296.3 ([M+H]+).

Sources & evidence

ORD record
ord-bc91dd8edde14b51b9bcece997db354f
Source dataset
uspto-grants-2006_06
Patent number
US07056932B2

Reaction notes

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