HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → HCID 22064679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | HCID 21905720 | HCID 21905720 | — |
| Reactant | α-Ethoxy-1,3-dihydro-4-methyl-1-oxo-2H-isoindole-2-acetic acid | HCID 22064727 | — |
| Product | HCID 22064679 | HCID 22064679 | — |
Reaction Steps
According to general procedure C, (RS)-ethoxy-(4-methyl-1-oxo-1,3-dihydro-isoindol-2-yl)-acetic acid (intermediate of example 44) was coupled with 4-aminomethyl-3-nitrobenzonitrile (CAS 701269-65-0) to give (RS)-N-(4-cyano-2-nitro-benzyl)-2-ethoxy-2-(4-methyl-1-oxo-1,3-dihydro-isoindol-2-yl)-acetamide as off-white crystals, MS 409.4 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07056932B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-0d14fdd7d3284b1ca31df3e25481180b |
| Source note | uspto-grants-2006_06 |