1,4-Dibromobutane → HCID 22064700, compound

HRID 1828108Notes

Reaction equation

HRID 1828108 reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][NH:7][C:8]2=[O:11])=[CH:4][CH:3]=1.Br[CH2:13][CH2:14][CH2:15][CH2:16]Br>>[N:1]1([C:2]2[CH:10]=[C:9]3[C:5]([CH2:6][NH:7][C:8]3=[O:11])=[CH:4][CH:3]=2)[CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 220646276-Amino-2,3-dihydro-1H-isoindol-1-one

Product 1

HCID 22064700HCID 22064700, compound

Procedure

The starting material 6-pyrrolidin-1-yl-2,3-dihydro-isoindol-1-one was prepared from 6-amino-2,3-dihydro-isoindol-1-one (CAS 675109-45-2) and 1,4-dibromobutane in analogy to the precedure described in example 56.

Sources & evidence

ORD record
ord-20a7ef9234264e66ac9dc58364cfcf29
Source dataset
uspto-grants-2006_06
Patent number
US07056932B2

Reaction notes

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