HCID 69585305, compound → HCID 69585305, compound

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Reaction Steps

5-[2-(1-Benzyl-piperidin-4-yl)-3-m-tolyl-1H-pyrazol-4-yl]-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one is prepared according to the procedures described in Example 334. 5-[2-(1-Benzyl-piperidin-4-yl)-3-m-tolyl-1H-pyrazol-4-yl]-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (180 mg) is diluted with ethanol (5 mL) and acetic acid (5 drops). The mixture is then treated with 5% Pd/C and shaken under an atmosphere of hydrogen for 8 hours. The mixture is then filtered and concentrated to give 1,3-Diethyl-5-(2-piperidin-4-yl-3-m-tolyl-1H-pyrazol-4-yl)-1,3-dihydro-benzoimidazol-2-one.

Provenance & Evidence