HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril → (S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril | HCID 9840862 | — |
| Reactant | (R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril | HCID 69194658 | — |
| Reactant | (R)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyril | HCID 69198597 | — |
| Product | (S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril | HCID 69196603 | — |
Reaction Steps
The title compound was prepared from (S)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyril (prepared in Example 5) by the procedures described for the preparation of (R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 7) from (R)-3-t-butyloxycarbonylamino-3,4-dihydrocarbostyril. HPLC/MS [M+H]+, 412.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07057046B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-7921178c7b72412f82aa438c4d22cd29 |
| Source note | uspto-grants-2006_06 |