Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1828351Generated: October 25, 2026

(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril → (r)-3-(5-Chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyril

https://huagongshe.com/reaction/1828351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 9840862—
Reactant(S)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 44357926—
Reactant(S)-3-(5-chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyrilHCID 87730389—
Product(r)-3-(5-Chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyrilHCID 87730651—

Reaction Steps

The title compound was prepared from (R)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 3) by the procedures described for the preparation of (S)-3-(5-chloroindole-2-carbonylamino)-1-cyanomethyl-3,4-dihydrocarbostyril (Example 17) from (S)-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril. HPLC/MS [M+H]+, 379.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07057046B2
Source datasetuspto-grants-2006_06
ORD IDord-0461bea1b7934e9992b0f9c6aeec7937
Source noteuspto-grants-2006_06