HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S, 3S)-3-(5-chloroindole-2-carbonylamino)-2-methyl-2,3-dihydro-1,5-benzoxazepin-4 (5H)-one → (2S, 3R)-3-(5-chloroindole-2-carbonylamino)-2-methyl-2,3-dihydro-1,5-benzoxazepin-4 (5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S, 3S)-3-(5-chloroindole-2-carbonylamino)-2-methyl-2,3-dihydro-1,5-benzoxazepin-4 (5H)-one | HCID 10067708 | — |
| Reactant | (2S, 3S)-3-amino-2-methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one trifluoroacetate salt | HCID 69195761 | — |
| Reactant | HCID 69196397 | HCID 69196397 | — |
| Product | (2S, 3R)-3-(5-chloroindole-2-carbonylamino)-2-methyl-2,3-dihydro-1,5-benzoxazepin-4 (5H)-one | HCID 11559723 | — |
Reaction Steps
The title compound was prepared from (2S,3R)-3-amino-2-methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one trifluoroacetate salt by the procedures described for the preparation of (2S,3S)-3-(5-chloroindole-2-carbonylamino)-2-methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one (Example 22) from (2S,3S)-3-amino-2-methyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one trifluoroacetate salt. HPLC/MS [M+H]+, 370.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07057046B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-30647d61ce9648eaaac37b9c952db602 |
| Source note | uspto-grants-2006_06 |