HCID 22063512, compound → HCID 22063606, compound

HRID 1828416Notes

Reaction equation

HRID 1828416 reaction equation
C([O:3][CH:4]1C[CH2:8][CH2:7][N:6]([C:10]2[N:11]=[C:12]3[CH:22]=[C:21]([CH2:23][CH2:24][C:25]4[S:26][CH:27]=[C:28]([CH:30]5[CH2:33][CH2:32][CH2:31]5)[N:29]=4)[CH:20]=[CH:19][N:13]3[C:14](=[O:18])[C:15]=2[CH:16]=[O:17])[CH2:5]1)=O.C1(C2N=C(CCC3C=CN4C(=O)C=C(N5CCOCC5)N=C4C=3)SC=2)CCC1>>[CH:30]1([C:28]2[N:29]=[C:25]([CH2:24][CH2:23][C:21]3[CH:20]=[CH:19][N:13]4[C:14](=[O:18])[C:15]([CH:16]=[O:17])=[C:10]([N:6]5[CH2:5][CH2:4][O:3][CH2:8][CH2:7]5)[N:11]=[C:12]4[CH:22]=3)[S:26][CH:27]=2)[CH2:33][CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 22063512HCID 22063512, compoundHCID 22063618HCID 22063618, compound

Product 1

HCID 22063606HCID 22063606, compoundYield 82%

Procedure

Reactions were performed in the same manner as in Example 1, (I) by using 8-[2-(4-cyclobutyl-1,3-thiazol-2-yl)ethyl]-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one (346 mg, 0.8726 mmol) to obtain 305 mg (82%) of the title compound as ocher solid.

Sources & evidence

ORD record
ord-3010abadfe5e4958b0a39f6fd9c79730
Source dataset
uspto-grants-2006_06
Patent number
US07056917B2

Reaction notes

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