HCID 22063608, compound → HCID 22063589, compound

HRID 1828422Notes

Reaction equation

HRID 1828422 reaction equation
[CH:1]([O:3][CH:4]1CC[CH2:7][N:6]([C:10]2[N:11]=[C:12]3[CH:22]=[C:21]([CH2:23][CH2:24][C:25]4[S:26][CH:27]=[C:28]([CH:30]5[CH2:33]CC5)[N:29]=4)[CH:20]=[CH:19][N:13]3[C:14](=[O:18])[C:15]=2[CH:16]=[O:17])[CH2:5]1)=O.C(C1N=C(CCC2C=CN3C(=O)C=C(N4CCOCC4)N=C3C=2)SC=1)C>>[CH2:30]([C:28]1[N:29]=[C:25]([CH2:24][CH2:23][C:21]2[CH:20]=[CH:19][N:13]3[C:14](=[O:18])[C:15]([CH:16]=[O:17])=[C:10]([N:6]4[CH2:7][CH2:1][O:3][CH2:4][CH2:5]4)[N:11]=[C:12]3[CH:22]=2)[S:26][CH:27]=1)[CH3:33]

Participants

3

Reactant 2

HCID 22063608HCID 22063608, compoundHCID 22063618HCID 22063618, compound

Product 1

HCID 22063589HCID 22063589, compoundYield 90%

Procedure

Reactions were performed in the same manner as in Example 1, (I) by using 8-[2-(4-ethyl-1,3-thiazol-2-yl)ethyl]-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one (120 mg, 0.324 mmol) to obtain 116 mg (90%) of the title compound.

Sources & evidence

ORD record
ord-62d926b2f1f94335bd4b3d402af6dd74
Source dataset
uspto-grants-2006_06
Patent number
US07056917B2

Reaction notes

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