HRID1828465

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2759334

(3R)-3-Piperidinol

C5H11NO

结构：CC(C)(C)c1csc(NC(=O)C2=CC3=NC(=O)CC(=O)N3C=C2)n1

HCID22063754

未命名化合物

结构：CC(C)(C)c1csc(NC(=O)c2ccn3c(=O)c(/C=C/C(=O)O)c(N4CCC[C@@H](O)C4)nc3c2)n1

HCID23581329

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1csc(NC(=O)c2ccn3c(=O)cc(N4CCC[C@@H](O)C4)nc3c2)n1

HCID23581334

未命名化合物

收率 65%

PROCEDURE

实验过程

Reactions were performed in the same manner as in Example 8, (E) by using N8-[4-(tert-butyl)-1,3-thiazol-2-yl]-2,4-dioxo-3,4-dihydro-2H-pyrido[1,2-a]pyrimidine-8-carboxamide (300 mg, 0.871 mmol) and (R)-(+)-3-hydroxypiperidine (530 mg, 5.226 mmol) to obtain 241.8 mg (65%) of the title compound.