N-Aminomorpholine → HCID 10155552, compound

HRID 1828564Notes

Reaction equation

[NH2:1][N:2]1[CH2:7][CH2:6][O:5][CH2:4][CH2:3]1.[C:8]1([C:14]2[N:15]=[C:16]([C:26](O)=[O:27])[N:17]([CH3:25])[C:18]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[N:2]1([NH:1][C:26]([C:16]2[N:17]([CH3:25])[C:18]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[N:15]=2)=[O:27])[CH2:7][CH2:6][O:5][CH2:4][CH2:3]1

Participants

Reactant 2

HCID 20315N-Aminomorpholine

HCID 22066062HCID 22066062, compound

Product 1

HCID 10155552HCID 10155552, compound

Procedure

Using essentially the same procedure as Example 4, Step B, but using 4-aminomorpholine (0.025 mL), 4,5-diphenyl-1-methylimidazole-2-carboxylic acid (30 mg, 0.10 mmol) from Example 4, Step A was converted to the title compound.

Sources & evidence

ORD record: ord-d25176d9c7a945bfac453bb76b8fd757
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07057051B2

Reaction notes

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